Research Groups and R&D Platforms: Preclinical development

R&D Platform:
Bioanalytical Laboratory for pharmacokinetic studies

Pharmacokinetic assessments and documentation of drug exposure are essential elements of all drug discovery and development endeavours. This research project aims to provide a technology platform for joint projects with investigators working in various fields of drug discovery and development. An automated system enabling frequent blood sampling from freely moving small laboratory animals and modern analytic instrumentation based on liquid chromatography and tandem mass spectrometry form the essential elements of this platform. Recent examples of the laboratory’s output are exemplified by the publications listed below, but a significant fraction of the laboratory’s projects represents contract research for small drug discovery companies. It is expected that this technology platform will help to promote both academic and commercial drug discovery and development activities in Finland.

Hit to lead, Lead optimization, Preclinical development

Research Group:
Computer-aided drug design

Outi Salo-Ahen

Pharmaceutical Sciences and Structural Bioinformatics Laboratory,
Åbo Akademi University

Antibacterial, Bioinformatics, Biomolecular chemistry, Biopharmaceuticals, Cancer, Drug target, Hit to lead, Infection, Lead optimization, Medicinal chemistry, Molecular modelling, Natural Compounds, Natural products, Pharmacy, Preclinical development, Screening, Structural Biology

Research Group:
BioNanoMaterials research group

Jessica Rosenholm

Pharmaceutical Sciences Laboratory,
Åbo Akademi University

Antibacterial, Biomedicine, Biopharmaceuticals, Biotechnology, Cancer, Diagnostics, Drug delivery, Drug solubility, Drug stability, Electron microscopy, Fluorescence spectroscopy, Formulation, FTIR or RAMAN spectroscopy, Imaging software, Infection, Lead optimization, Musculoskeletal disorders, Nanoparticles, Natural products, Organic compounds, Particle morphology, Particle size analysis, Personalized medicine, Pharmacy, Physico-chemical properties, Porosity, Powder flow characterization, Powder X-ray diffraction, Preclinical development, Screening, Skin diseases, Super-resolution imaging, Surface area, Synthetic chemistry, Thermal analysis, Zeta potential