Research Groups and R&D Platforms: Assay development

Research Group:
Gas and biosensors

Jouko Peltonen
jouko.peltonen[at]abo.fi

Laboratory of physical chemistry,
Åbo Akademi University

Jouko Peltonen

Antibacterial, Antibodies, Assay development, Atomic-force microscopy, Diagnostics, Electron microscopy, Formulation, In Vitro Diagnostics, Inflammation, Molecular diagnostics, Nanoparticles, Organic compounds, Particle size analysis, Personalized medicine, Pharmacy, Physico-chemical properties, Point of care, Porosity, Surface area, Zeta potential

Research Group:
New methods and biomarkers for IBD

Harri Siitari
harri.siitari[at]utu.fi

Laboratory of Medical physics,
University of Turku

Harri Siitari

Biomarkers and decision support tools for personalized diagnostics and care

Assay development, Autoimmune diseases, Biomarker, Biomedicine, Biotechnology, Data mining, Diagnostics, In Vitro Diagnostics, Inflammation, Molecular diagnostics, Neurological disorders, NMR, Personalized medicine

Research Group:
High Content Screening Laboratory

Matthias Nees (Principal Investigator)

Malin Åkerfelt (Contact person, in picture)
malake[at]utu.fi

Institute of Biomedicine,
Univesity of Turku

Matthias Nees

Malin Åkerfelt

HCSLab

Assay development, Bioinformatics, Biomedicine, Biotechnology, Breast cancer, Cancer, Disease models, Drug target, High throughput imaging, Hit to lead, Imaging, Inflammation, Lead optimization, Lung cancer, Machine learning, Molecular Cell Biology, Natural Compounds, Prostate cancer, Screening, Target discovery

Research Group:
Laboratory of Biophysics

Pekka Hänninen
pekka.e.hanninen[at]utu.fi

Institute of Biomedicine,
University of Turku

Pekka Hänninen

Assay development, Atomic-force microscopy, Biomolecular chemistry, Cancer, Data mining, Diabetes, Diagnostics, Fluorescence spectroscopy, Imaging, In Vitro Diagnostics, Machine learning, Nanoparticles, Physics, Super-resolution imaging

Picture of Ilkka Julkunen

Research Group:
Innate and adaptive immunity in viral infections

Ilkka Julkunen
ilkka.julkunen[at]utu.fi

Institute of Biomedicine
University of Turku

Ilkka Julkunen

Antibodies, Assay development, Autoimmune diseases, Basic research, Biomarker, Biomedicine, Biotechnology, Diagnostics, Imaging, Imaging software, Immunology, In Vitro Diagnostics, Infection, Inflammation, Medicinal chemistry, Molecular Biology, Molecular Cell Biology, Molecular diagnostics, Molecular modelling, Neurological disorders, Pattern recognition, Proteomics, Receptor, Signaling, Virology

R&D Platform:
Screening Unit

The screening unit offers academic researchers and industrial customers a broad range of services for identifying and optimising bioactive molecules for the drug discovery process. These include molecular modelling and in silico screening, development of screening assays and compound library screens, in vitro and in situ hit validation, hit optimisation and SAR analyses. A suite of cell and tissue-based disease models for oncology and neurological diseases are available for further validation of optimised hits or for independent phenotypic screens. High-throughput kinetic assays of changes in morphology or intracellular signalling over time may be integrated into chemical, genetic or optogenetic perturbation screens. A library of reporters in gene-delivery vectors are available for this purpose. The unit also has experience performing screens and toxicological evaluations in small animal models.

Contact details

Screening Unit

High-throughput screens, screen-compatible assays, high-throughput microscopy, libraries, optogenetics, cell-based neurological disease models:
michael.courtney[at]utu.fi

3D oncology models, phenotypic screens, high-content screens:
malin.akerfelt[at]utu.fi

Medicinal chemistry, virtual screening and molecular modelling:
olli.pentikainen[at]utu.fi

Assay development, Basic research, Disease models, High throughput imaging, Hit to lead, Lead optimization, Medicinal chemistry, Molecular modelling, R&D Platforms, Screening, Signaling, Target discovery